I use this for college work, mostly Cisco Packet Tracer Simulations also a bit of gaming. The main problem I have is that my current case is crap but I live in a 3rd world country so getting anything fancy is out of the question. A cruddy Logisys case is $150 US + at the local computer store.
Another thing, my case doesn't support 2.5 drives so I had to fabricate something to hold my back-up HDD.
The major problem I have is that air cooling isnt great for me as the temps down here are always 80 F + but overall I love my PC =]