I use my machine mostly for web, some video watching, videogames and web development. Had a bit of dilemma with the case fan arrangement for the water cooling, but after some google-fu decided to mount the fans at the front as intake and the one at the rear by the radiator as an exhaust. So far the airflow in the case seems to be doing the job, I am considering adding a second fan to the inner-side of the radiator to get more of a push-pull thing going on.
By a happy fluke I managed to end up with 2 x 128GB SSDs, but only had one mounting tray so I have one sat in the tray and the other one screwed in underneath. I reasoned that while it would be better to have a dedicated bay for each drive, they were both positioned right next to the front intake fans so should remain cool enough and not having to have the second drive rack in the case would help with airflow too.
The only other thing was that by default the DDR3 1600 RAM I had bought was operating only at 1333Mhz, so I had to go into the AI settings and manually set this to 1600Mhz.
So far so good... I've tried a few games like Assassin's Creed 3 (Which came free with my Video Card) and Battlefield 3 and am not quite reach 60FPS at highest detail settings, but compared to what I was getting on my old Xbox 360, it's a huge improvement in fidelity and frame-rate overall...