I use this for: Gaming Recording Video Editing/Rendering Coding
and whatever else floats my boat.
Really no problems to speak of hardware-wise.
Software wise - I had to do a full system restore and reinstall drivers to figure out why the screen was stuck in low power mode. Turns out that ASUS GPU Tweak doesn't play nicely with other programs. And NVIDIA's control panel switched my display to an unsupported resolution after going to sleep, so it wouldn't display anything until I switched out the input to HDMI instead of DVI. Freaked out and thought the DVI cable was bad, bought a new one, eventually figured it out.
It runs a bit hot when running things on 4k/Ultra settings, but it's also summer right now, so it'll be nice in the winter.
Also, through various promotions and deals, I think the final cost to me for all of this was about $2,800 instead of the listed $3,400.
(I'll post more pictures later)