This was a build to replace an old Thinkpad T420 with a Sandy Bridge and no discrete graphics for video production, photo production... and to play Fallout 4, lol. I also needed to be able to cart it in my car to the office, but needed at least two accessible PCI-E slots for a video card and Wi-Fi card, so that meant mATX.
For the most part, price-to-performance was key. The RX 480 -- as there was no GTX 1060 when I bought these parts, and there still isn't now weeks later -- is the price-to-performance king. About equal with a GTX 970 for a GTX 960's price. I needed a video card now, and that meant the RX 480. No problems on this motherboard, as it's not a piece of crap.
I could have gone with a cheaper board, but I went with a Z170 board to future-proof the board -- I can toss an i7-K into it in the future for more power, as well as even more RAM and a faster video card to keep this rig going for years.Add in M.2 support and USB 3.1, I don't see anything in the immediate future that will make this incapable of working for what I need.
I originally built this rig in May in an old eMachines case, but wanted something nicer that had 120mm fan support, so I grabbed an N200 -- I considered a Thermaltake Core V21, but they were out of stock when I went shopping. This case, while probably not as nice from a cable management perspective and from a "ooh, look at the goodies" perspective, lets me keep an optical drive, a smaller footprint on the desk and a cheaper price.