Used mainly for general engineering: IPython, Matlab, Java/C++, Ansys, Solidworks. Also, steam (all TW games, CivV, Tomb Raider on extreme settings is really smooth).
The Xeon processor is a dream. Hyperthreading for all that CAD at an i5 price. I've been really impressed with the 750ti, as it runs very cool even at max performance: a smooth, cool cat with a kick-*** bite.
I'm running Windows 8.1 and Ubuntu 14.04 in dual-boot on the SSD, with symlinks to all of my files on the HDD. It's been fantastic so far, but just remember Ninite.com does not allow you to install to the non-OS drive.
On the down-side, make sure to have an extension and/or splitter for the PWM fam in front. The cable wasn't long enough for a gentle connection with the Mobo, and there are only 2 4-pun slots on the board. Fine with me, the splitter from fry's was just right.
I'm also getting a very quiet, very high-pitched whine from the HDD, but nothing I can't live with once everything is in a proper desk. I'm using my old Acer H388H 23" monitor in the pics, but the new Asus is FANTASTIC. So...much...productivity.... tear