Yes, you can buy an internal usb connector cable or even an internal adapter without the cable part. They are usually only 2-5 euros/dollars.
That being said, looping the cable outside the case doesn't look as weird as it sounds, because it's still only small part of the mess behind a case. You can see two of them in this photo of mine: https://www.dropbox.com/s/2z3f8c6gpbntkih/20180322_170843.jpg?raw=1
The larger HDMI in the marked section goes to front/top panel for VR use. The info display HDMI is the tiny cable behind it.
Yeah, its more about using up a port since I do 3 monitors, than it is about using HDMi vs. another solution.
I guess I need to see if I can do USB 2.0/3.1 to HDMI and have that supply video AND power. Either that, or I'd have to got the internal hub route and use one port for power, one for USB-> HDMI
Have never done USB to video, so that'll be a first for me, setting it up.